Continued Benefit of Coronary Stenting Versus Balloon Angioplasty: One-Year Cliqieal Foll~w4Jp of Benestent Trial

Ob~ves. ‘I&is study sougkt to determine the l-year clinical follow-up of patients iucluded in the Benesteot trial. Racw. The Benestent trial is a nmdomized study comparing ekctlle Palmaz-Sekatz stent implautatioo with baIlooa angioplasty in patients with stable augina and a de aovo coronary arkry lesion. Seven-month bllow-up data have shown a decreased rate of resteaasis and fewer cliaifal events in tke steut group. It is not establisked wketber this favorable clhdcal auteome is maIntaioed for longer periods or wketber cmunary steatiag defers restenosis and its subsqueut clioical manifestatbus. Mefhodv. To ckuify this oncednty, we updated clinical ioformation on all but I of 516 patients enrolled in tke Beuestent trial (257 in balloon group, 259 ia stent group) at least 12 ma&s after the intervention. Major clinical events (primary cliuical end point) were tabulated aeeordiug to tbe intention to treat priuciple and included de&, tke oeearreace of a cehvaxular accident, mytnxrdial in&r&u, the need for bypass surgery or a liuiber percutaneous intervention in the previously treated lesion. Results. After 1 year, uo significant dikreuces in mortality (1.2% vs. 0.8%), stroke (0.0% vs. 0.8%). myocardial infarction (5.0% vs. 4.2%) or eoroaary bypass graft surgery (6.9% vs. 5.1%) were found between tke stent aad ballooa aagioplasty groups, respectiveIy. However, tke requirement for a repeat angioplasty prwcedure was sigailicantly lower ia tbe steut group (10%) than tbe balloaa angbphsty group (2196, rehtive risk [RR] 0.49,95% coafMie.ace interval ICI] 031 ta 0.75, p = O.OOl), aud overall primary end points w less frequeatly reacked by stent group patients (23.2%) than those in the baMoon group (315%, RR 0.74, 95% CI 055 to O.%, p = 0.64). No diiereaces were fouad between groups with respect to fi~octkmal class aagina and prescribed medIItioa at tke time of follow-up. ConeLLFiofis. Tkese clinical follow-up data show that UK benefit of elective aative conmary artery steating in patients with stable auginais-toatIeastlyearaflertbepbeedurraud resaltsiaasi@&aatlyrPdmdreqoirrareotfarrepeatintmeatia CJAm Cdl Gdid l!W6;27:2S-61)